Monday, May 6, 2013

MANUEL ELKIN PATARROYO


• TOP 3:    MANUEL ELKIN PATARROYO

He was born March 11, 1946 is a Colombian pathologist who made the world's first attempt of synthetic vaccine for malaria, a disease transmitted by mosquitoes that affects millions of people in tropical and subtropical regions, including parts of the Americas, Asia, and Africa.

 The vaccine candidate, first developed in 1987, was evaluated in clinical trials carried out by the WHO in Gambia, Tanzania and Thailand, and had mixed results. In 2009, a comprehensive Cochrane review assessed the SPf66 as being not efficacious in Africa and Asia, and as having a low but statistically significant efficacy of 28% in South America. Today, after more than 33 years of research, the SPf66 malaria vaccine is not recommended for prophylaxis of malaria and is listed as "inactive" by the WHO.

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